Does TOPIRAMATE Cause Necrotising colitis? 56 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 56 reports of Necrotising colitis have been filed in association with TOPIRAMATE (Topiramate). This represents 0.2% of all adverse event reports for TOPIRAMATE.
56
Reports of Necrotising colitis with TOPIRAMATE
0.2%
of all TOPIRAMATE reports
1
Deaths
10
Hospitalizations
How Dangerous Is Necrotising colitis From TOPIRAMATE?
Of the 56 reports, 1 (1.8%) resulted in death, 10 (17.9%) required hospitalization, and 24 (42.9%) were considered life-threatening.
Is Necrotising colitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOPIRAMATE. However, 56 reports have been filed with the FAERS database.
What Other Side Effects Does TOPIRAMATE Cause?
Drug ineffective (5,553)
Off label use (4,248)
Product use in unapproved indication (2,173)
Headache (1,997)
Drug intolerance (1,820)
Migraine (1,796)
Nausea (1,691)
Seizure (1,535)
Paraesthesia (1,506)
Dizziness (1,466)
What Other Drugs Cause Necrotising colitis?
IBUPROFEN (101)
QUETIAPINE (40)
CYCLOPHOSPHAMIDE (36)
PREDNISOLONE (31)
TACROLIMUS (31)
METHOTREXATE (30)
DOXORUBICIN (29)
PREDNISONE (28)
TROPATEPINE (28)
RITUXIMAB (27)
Which TOPIRAMATE Alternatives Have Lower Necrotising colitis Risk?
TOPIRAMATE vs TOPOTECAN
TOPIRAMATE vs TOPOTECAN\TOPOTECAN
TOPIRAMATE vs TOPROL
TOPIRAMATE vs TOREMIFENE
TOPIRAMATE vs TORIPALIMAB