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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Necrotising colitis: Which Medications Cause It? (795 Reports Across 90 Drugs)

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Necrotising colitis has been reported as an adverse event with 90 different drugs in the FDA's FAERS database, with 795 total reports. 245 of these reports resulted in death.The drugs most commonly associated with Necrotising colitis are IBUPROFEN, TOPIRAMATE, and QUETIAPINE.

795
Total Reports
90
Drugs Involved
245
Deaths
344
Hospitalizations
42.4 yrs
Average Patient Age
48.8% / 51.2%
Female / Male

Which Drugs Cause Necrotising colitis Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
IBUPROFEN 101 0.1% 26 25 10
TOPIRAMATE 56 0.2% 1 10 24
QUETIAPINE 40 0.1% 17 25 16
CYCLOPHOSPHAMIDE 36 0.0% 16 28 20
PREDNISOLONE 31 0.0% 7 23 7
TACROLIMUS 31 0.0% 8 20 5
METHOTREXATE 30 0.0% 9 19 6
DOXORUBICIN 29 0.0% 17 21 18
PREDNISONE 28 0.0% 16 24 18
TROPATEPINE 28 1.9% 15 24 17
RITUXIMAB 27 0.0% 21 15 14
VINCRISTINE 27 0.0% 16 17 14
LOXAPINE 25 0.6% 17 20 19
DIAZEPAM 24 0.1% 14 20 17
INDOMETHACIN 24 0.5% 6 7 1
BEVACIZUMAB 23 0.0% 13 14 0
OCTREOTIDE 23 0.1% 10 5 1
METHADONE 21 0.1% 0 12 4
ACETAMINOPHEN 20 0.0% 8 7 1
HYDROCORTISONE 20 0.1% 4 8 5

View all 90 drugs →

Top 3 Drugs Associated With Necrotising colitis

101 reports
56 reports
40 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)