Does TOPOTECAN Cause Febrile neutropenia? 425 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 425 reports of Febrile neutropenia have been filed in association with TOPOTECAN (HYCAMTIN). This represents 12.0% of all adverse event reports for TOPOTECAN.
425
Reports of Febrile neutropenia with TOPOTECAN
12.0%
of all TOPOTECAN reports
21
Deaths
330
Hospitalizations
How Dangerous Is Febrile neutropenia From TOPOTECAN?
Of the 425 reports, 21 (4.9%) resulted in death, 330 (77.6%) required hospitalization, and 98 (23.1%) were considered life-threatening.
Is Febrile neutropenia Listed in the Official Label?
Yes, Febrile neutropenia is listed as a known adverse reaction in the official FDA drug label for TOPOTECAN.
What Other Side Effects Does TOPOTECAN Cause?
Off label use (390)
Death (332)
Product use in unapproved indication (323)
Neutropenia (255)
Pyrexia (252)
Anaemia (242)
Malignant neoplasm progression (238)
Drug ineffective (216)
Disease progression (207)
Thrombocytopenia (207)
What Other Drugs Cause Febrile neutropenia?
CYCLOPHOSPHAMIDE (11,318)
DOXORUBICIN (8,844)
VINCRISTINE (8,676)
RITUXIMAB (6,382)
CYTARABINE (6,142)
METHOTREXATE (6,091)
ETOPOSIDE (5,966)
CARBOPLATIN (4,888)
DEXAMETHASONE (4,382)
PREDNISONE (3,956)
Which TOPOTECAN Alternatives Have Lower Febrile neutropenia Risk?
TOPOTECAN vs TOPOTECAN\TOPOTECAN
TOPOTECAN vs TOPROL
TOPOTECAN vs TOREMIFENE
TOPOTECAN vs TORIPALIMAB
TOPOTECAN vs TORSEMIDE