Does TOPOTECAN Cause Neutropenia? 255 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 255 reports of Neutropenia have been filed in association with TOPOTECAN (HYCAMTIN). This represents 7.2% of all adverse event reports for TOPOTECAN.
255
Reports of Neutropenia with TOPOTECAN
7.2%
of all TOPOTECAN reports
34
Deaths
147
Hospitalizations
How Dangerous Is Neutropenia From TOPOTECAN?
Of the 255 reports, 34 (13.3%) resulted in death, 147 (57.6%) required hospitalization, and 40 (15.7%) were considered life-threatening.
Is Neutropenia Listed in the Official Label?
Yes, Neutropenia is listed as a known adverse reaction in the official FDA drug label for TOPOTECAN.
What Other Side Effects Does TOPOTECAN Cause?
Febrile neutropenia (425)
Off label use (390)
Death (332)
Product use in unapproved indication (323)
Pyrexia (252)
Anaemia (242)
Malignant neoplasm progression (238)
Drug ineffective (216)
Disease progression (207)
Thrombocytopenia (207)
What Other Drugs Cause Neutropenia?
CLOZAPINE (18,981)
CYCLOPHOSPHAMIDE (7,352)
LENALIDOMIDE (6,909)
RITUXIMAB (6,607)
PALBOCICLIB (6,423)
DEXAMETHASONE (6,050)
DOXORUBICIN (5,891)
CARBOPLATIN (5,314)
VINCRISTINE (4,982)
PACLITAXEL (4,553)
Which TOPOTECAN Alternatives Have Lower Neutropenia Risk?
TOPOTECAN vs TOPOTECAN\TOPOTECAN
TOPOTECAN vs TOPROL
TOPOTECAN vs TOREMIFENE
TOPOTECAN vs TORIPALIMAB
TOPOTECAN vs TORSEMIDE