TOPOTECAN\TOPOTECAN for Nephroblastoma: Side Effects & Safety Data
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There are 28 adverse event reports in the FDA FAERS database where TOPOTECAN\TOPOTECAN was used for Nephroblastoma.
Most Reported Side Effects for TOPOTECAN\TOPOTECAN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Disease progression | 111 | 21.7% | 64 | 3 |
| Neutropenia | 44 | 8.6% | 4 | 4 |
| Drug resistance | 35 | 6.9% | 34 | 0 |
| Mucosal inflammation | 24 | 4.7% | 4 | 6 |
| Bone marrow failure | 23 | 4.5% | 10 | 3 |
| Bronchospasm | 23 | 4.5% | 0 | 0 |
| Malignant neoplasm progression | 22 | 4.3% | 10 | 2 |
| Nausea | 20 | 3.9% | 10 | 10 |
| Anaemia | 18 | 3.5% | 4 | 10 |
| Hypertension | 18 | 3.5% | 1 | 2 |
| Infection | 18 | 3.5% | 3 | 1 |
| Pancytopenia | 18 | 3.5% | 6 | 9 |
| Death | 17 | 3.3% | 17 | 1 |
| Off label use | 17 | 3.3% | 4 | 2 |
| Febrile neutropenia | 16 | 3.1% | 6 | 6 |
Other Indications for TOPOTECAN\TOPOTECAN
Retinoblastoma (86)
Ovarian cancer (70)
Neuroblastoma (53)
Small cell lung cancer (19)
Cervix carcinoma (17)
Neoplasm (17)
Congenital retinoblastoma (16)
Product used for unknown indication (16)
Bone marrow conditioning regimen (12)
Ewing's sarcoma (10)
Other Drugs Used for Nephroblastoma
VINCRISTINE (375)
DOXORUBICIN (345)
ETOPOSIDE (286)
DACTINOMYCIN (278)
CARBOPLATIN (228)
CYCLOPHOSPHAMIDE (217)
IRINOTECAN (104)
IFOSFAMIDE (100)
MELPHALAN (36)
TEMOZOLOMIDE (26)