TOPOTECAN\TOPOTECAN for Bone marrow conditioning regimen: Side Effects & Safety Data
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There are 12 adverse event reports in the FDA FAERS database where TOPOTECAN\TOPOTECAN was used for Bone marrow conditioning regimen.
Most Reported Side Effects for TOPOTECAN\TOPOTECAN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Disease progression | 111 | 21.7% | 64 | 3 |
| Neutropenia | 44 | 8.6% | 4 | 4 |
| Drug resistance | 35 | 6.9% | 34 | 0 |
| Mucosal inflammation | 24 | 4.7% | 4 | 6 |
| Bone marrow failure | 23 | 4.5% | 10 | 3 |
| Bronchospasm | 23 | 4.5% | 0 | 0 |
| Malignant neoplasm progression | 22 | 4.3% | 10 | 2 |
| Nausea | 20 | 3.9% | 10 | 10 |
| Anaemia | 18 | 3.5% | 4 | 10 |
| Hypertension | 18 | 3.5% | 1 | 2 |
| Infection | 18 | 3.5% | 3 | 1 |
| Pancytopenia | 18 | 3.5% | 6 | 9 |
| Death | 17 | 3.3% | 17 | 1 |
| Off label use | 17 | 3.3% | 4 | 2 |
| Febrile neutropenia | 16 | 3.1% | 6 | 6 |
Other Indications for TOPOTECAN\TOPOTECAN
Retinoblastoma (86)
Ovarian cancer (70)
Neuroblastoma (53)
Nephroblastoma (28)
Small cell lung cancer (19)
Cervix carcinoma (17)
Neoplasm (17)
Congenital retinoblastoma (16)
Product used for unknown indication (16)
Ewing's sarcoma (10)
Other Drugs Used for Bone marrow conditioning regimen
FLUDARABINE (6,080)
BUSULFAN (4,669)
CYCLOPHOSPHAMIDE (4,485)
MELPHALAN (2,368)
LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN (1,884)
THIOTEPA (1,551)
ALEMTUZUMAB (1,122)
ETOPOSIDE (936)
CYTARABINE (833)
THYMOCYTE IMMUNE GLOBULIN NOS (742)