THIOTEPA for Bone marrow conditioning regimen: Side Effects & Safety Data
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There are 1,551 adverse event reports in the FDA FAERS database where THIOTEPA was used for Bone marrow conditioning regimen.
Most Reported Side Effects for THIOTEPA
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 762 | 11.2% | 187 | 142 |
| Febrile neutropenia | 645 | 9.4% | 89 | 144 |
| Mucosal inflammation | 616 | 9.0% | 93 | 131 |
| Cytomegalovirus infection | 446 | 6.5% | 87 | 48 |
| Product use in unapproved indication | 425 | 6.2% | 86 | 63 |
| Pyrexia | 359 | 5.3% | 74 | 147 |
| Drug ineffective | 358 | 5.2% | 77 | 101 |
| Acute graft versus host disease in skin | 355 | 5.2% | 70 | 51 |
| Acute graft versus host disease | 331 | 4.8% | 98 | 36 |
| Cytomegalovirus infection reactivation | 325 | 4.8% | 57 | 56 |
| Infection | 318 | 4.7% | 218 | 7 |
| Venoocclusive liver disease | 306 | 4.5% | 115 | 59 |
| Thrombocytopenia | 297 | 4.3% | 47 | 65 |
| Neutropenia | 288 | 4.2% | 79 | 44 |
| Sepsis | 271 | 4.0% | 138 | 53 |
Other Indications for THIOTEPA
Allogenic stem cell transplantation (1,476)
Stem cell transplant (799)
Central nervous system lymphoma (396)
Diffuse large b-cell lymphoma (335)
Autologous haematopoietic stem cell transplant (275)
Product used for unknown indication (258)
Prophylaxis against transplant rejection (195)
Medulloblastoma (184)
Chemotherapy (181)
Immunosuppressant drug therapy (121)
Other Drugs Used for Bone marrow conditioning regimen
FLUDARABINE (6,080)
BUSULFAN (4,669)
CYCLOPHOSPHAMIDE (4,485)
MELPHALAN (2,368)
LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN (1,884)
ALEMTUZUMAB (1,122)
ETOPOSIDE (936)
CYTARABINE (833)
THYMOCYTE IMMUNE GLOBULIN NOS (742)
TREOSULFAN (695)