THIOTEPA for Stem cell transplant: Side Effects & Safety Data
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There are 799 adverse event reports in the FDA FAERS database where THIOTEPA was used for Stem cell transplant.
Most Reported Side Effects for THIOTEPA
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 762 | 11.2% | 187 | 142 |
| Febrile neutropenia | 645 | 9.4% | 89 | 144 |
| Mucosal inflammation | 616 | 9.0% | 93 | 131 |
| Cytomegalovirus infection | 446 | 6.5% | 87 | 48 |
| Product use in unapproved indication | 425 | 6.2% | 86 | 63 |
| Pyrexia | 359 | 5.3% | 74 | 147 |
| Drug ineffective | 358 | 5.2% | 77 | 101 |
| Acute graft versus host disease in skin | 355 | 5.2% | 70 | 51 |
| Acute graft versus host disease | 331 | 4.8% | 98 | 36 |
| Cytomegalovirus infection reactivation | 325 | 4.8% | 57 | 56 |
| Infection | 318 | 4.7% | 218 | 7 |
| Venoocclusive liver disease | 306 | 4.5% | 115 | 59 |
| Thrombocytopenia | 297 | 4.3% | 47 | 65 |
| Neutropenia | 288 | 4.2% | 79 | 44 |
| Sepsis | 271 | 4.0% | 138 | 53 |
Other Indications for THIOTEPA
Bone marrow conditioning regimen (1,551)
Allogenic stem cell transplantation (1,476)
Central nervous system lymphoma (396)
Diffuse large b-cell lymphoma (335)
Autologous haematopoietic stem cell transplant (275)
Product used for unknown indication (258)
Prophylaxis against transplant rejection (195)
Medulloblastoma (184)
Chemotherapy (181)
Immunosuppressant drug therapy (121)
Other Drugs Used for Stem cell transplant
BUSULFAN (1,700)
FLUDARABINE (1,601)
CYCLOPHOSPHAMIDE (1,262)
CYCLOSPORINE (1,251)
MYCOPHENOLATE MOFETIL (938)
MELPHALAN (738)
TACROLIMUS (600)
METHOTREXATE (481)
LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN (442)
ALEMTUZUMAB (235)