MELPHALAN for Stem cell transplant: Side Effects & Safety Data
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There are 738 adverse event reports in the FDA FAERS database where MELPHALAN was used for Stem cell transplant.
Most Reported Side Effects for MELPHALAN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 2,002 | 12.5% | 437 | 495 |
| Febrile neutropenia | 931 | 5.8% | 145 | 419 |
| Drug ineffective | 853 | 5.3% | 199 | 213 |
| Neutropenia | 810 | 5.0% | 145 | 246 |
| Mucosal inflammation | 804 | 5.0% | 131 | 254 |
| Plasma cell myeloma | 781 | 4.9% | 223 | 99 |
| Product use in unapproved indication | 765 | 4.8% | 144 | 182 |
| Thrombocytopenia | 701 | 4.4% | 118 | 253 |
| Diarrhoea | 698 | 4.4% | 95 | 343 |
| Pyrexia | 667 | 4.2% | 144 | 346 |
| Pneumonia | 650 | 4.1% | 254 | 382 |
| Disease progression | 595 | 3.7% | 155 | 90 |
| Myelodysplastic syndrome | 573 | 3.6% | 231 | 132 |
| Sepsis | 544 | 3.4% | 316 | 247 |
| Venoocclusive liver disease | 464 | 2.9% | 152 | 130 |
Other Indications for MELPHALAN
Plasma cell myeloma (4,878)
Bone marrow conditioning regimen (2,368)
Product used for unknown indication (963)
Retinoblastoma (715)
Diffuse large b-cell lymphoma (595)
Neuroblastoma (495)
Allogenic stem cell transplantation (374)
Hodgkin's disease (351)
Autologous haematopoietic stem cell transplant (284)
Chemotherapy (284)
Other Drugs Used for Stem cell transplant
BUSULFAN (1,700)
FLUDARABINE (1,601)
CYCLOPHOSPHAMIDE (1,262)
CYCLOSPORINE (1,251)
MYCOPHENOLATE MOFETIL (938)
THIOTEPA (799)
TACROLIMUS (600)
METHOTREXATE (481)
LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN (442)
ALEMTUZUMAB (235)