MELPHALAN for Diffuse large b-cell lymphoma: Side Effects & Safety Data
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There are 595 adverse event reports in the FDA FAERS database where MELPHALAN was used for Diffuse large b-cell lymphoma.
Most Reported Side Effects for MELPHALAN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 2,002 | 12.5% | 437 | 495 |
| Febrile neutropenia | 931 | 5.8% | 145 | 419 |
| Drug ineffective | 853 | 5.3% | 199 | 213 |
| Neutropenia | 810 | 5.0% | 145 | 246 |
| Mucosal inflammation | 804 | 5.0% | 131 | 254 |
| Plasma cell myeloma | 781 | 4.9% | 223 | 99 |
| Product use in unapproved indication | 765 | 4.8% | 144 | 182 |
| Thrombocytopenia | 701 | 4.4% | 118 | 253 |
| Diarrhoea | 698 | 4.4% | 95 | 343 |
| Pyrexia | 667 | 4.2% | 144 | 346 |
| Pneumonia | 650 | 4.1% | 254 | 382 |
| Disease progression | 595 | 3.7% | 155 | 90 |
| Myelodysplastic syndrome | 573 | 3.6% | 231 | 132 |
| Sepsis | 544 | 3.4% | 316 | 247 |
| Venoocclusive liver disease | 464 | 2.9% | 152 | 130 |
Other Indications for MELPHALAN
Plasma cell myeloma (4,878)
Bone marrow conditioning regimen (2,368)
Product used for unknown indication (963)
Stem cell transplant (738)
Retinoblastoma (715)
Neuroblastoma (495)
Allogenic stem cell transplantation (374)
Hodgkin's disease (351)
Autologous haematopoietic stem cell transplant (284)
Chemotherapy (284)
Other Drugs Used for Diffuse large b-cell lymphoma
RITUXIMAB (22,275)
CYCLOPHOSPHAMIDE (16,598)
DOXORUBICIN (15,213)
VINCRISTINE (14,922)
PREDNISONE (11,266)
LENALIDOMIDE (7,858)
ETOPOSIDE (4,698)
PREDNISOLONE (4,086)
CYTARABINE (3,857)
DEXAMETHASONE (3,696)