Does MELPHALAN Cause Sepsis? 544 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 544 reports of Sepsis have been filed in association with MELPHALAN (Melphalan Hydrochloride). This represents 3.4% of all adverse event reports for MELPHALAN.
544
Reports of Sepsis with MELPHALAN
3.4%
of all MELPHALAN reports
316
Deaths
247
Hospitalizations
How Dangerous Is Sepsis From MELPHALAN?
Of the 544 reports, 316 (58.1%) resulted in death, 247 (45.4%) required hospitalization, and 87 (16.0%) were considered life-threatening.
Is Sepsis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MELPHALAN. However, 544 reports have been filed with the FAERS database.
What Other Side Effects Does MELPHALAN Cause?
Off label use (2,002)
Febrile neutropenia (931)
Drug ineffective (853)
Neutropenia (810)
Mucosal inflammation (804)
Plasma cell myeloma (781)
Product use in unapproved indication (765)
Thrombocytopenia (701)
Diarrhoea (698)
Pyrexia (667)
What Other Drugs Cause Sepsis?
RITUXIMAB (4,043)
CYCLOPHOSPHAMIDE (4,041)
METHOTREXATE (3,933)
ADALIMUMAB (3,169)
DEXAMETHASONE (3,150)
LENALIDOMIDE (2,956)
VINCRISTINE (2,791)
DOXORUBICIN (2,740)
PREDNISONE (2,634)
PREDNISOLONE (2,281)
Which MELPHALAN Alternatives Have Lower Sepsis Risk?
MELPHALAN vs MEMANTINE
MELPHALAN vs MENINGOCOCCAL GROUP B VACCINE
MELPHALAN vs MENINGOCOCCAL POLYSACCHARIDE VACCINE A\NEISSERIA MENINGITIDIS GROUP A CAPSULAR POLYSACCHARIDE ANTIGEN
MELPHALAN vs MENOTROPINS
MELPHALAN vs MENTHOL