MELPHALAN for Bone marrow conditioning regimen: Side Effects & Safety Data
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There are 2,368 adverse event reports in the FDA FAERS database where MELPHALAN was used for Bone marrow conditioning regimen.
Most Reported Side Effects for MELPHALAN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 2,002 | 12.5% | 437 | 495 |
| Febrile neutropenia | 931 | 5.8% | 145 | 419 |
| Drug ineffective | 853 | 5.3% | 199 | 213 |
| Neutropenia | 810 | 5.0% | 145 | 246 |
| Mucosal inflammation | 804 | 5.0% | 131 | 254 |
| Plasma cell myeloma | 781 | 4.9% | 223 | 99 |
| Product use in unapproved indication | 765 | 4.8% | 144 | 182 |
| Thrombocytopenia | 701 | 4.4% | 118 | 253 |
| Diarrhoea | 698 | 4.4% | 95 | 343 |
| Pyrexia | 667 | 4.2% | 144 | 346 |
| Pneumonia | 650 | 4.1% | 254 | 382 |
| Disease progression | 595 | 3.7% | 155 | 90 |
| Myelodysplastic syndrome | 573 | 3.6% | 231 | 132 |
| Sepsis | 544 | 3.4% | 316 | 247 |
| Venoocclusive liver disease | 464 | 2.9% | 152 | 130 |
Other Indications for MELPHALAN
Plasma cell myeloma (4,878)
Product used for unknown indication (963)
Stem cell transplant (738)
Retinoblastoma (715)
Diffuse large b-cell lymphoma (595)
Neuroblastoma (495)
Allogenic stem cell transplantation (374)
Hodgkin's disease (351)
Autologous haematopoietic stem cell transplant (284)
Chemotherapy (284)
Other Drugs Used for Bone marrow conditioning regimen
FLUDARABINE (6,080)
BUSULFAN (4,669)
CYCLOPHOSPHAMIDE (4,485)
LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN (1,884)
THIOTEPA (1,551)
ALEMTUZUMAB (1,122)
ETOPOSIDE (936)
CYTARABINE (833)
THYMOCYTE IMMUNE GLOBULIN NOS (742)
TREOSULFAN (695)