MELPHALAN for Allogenic stem cell transplantation: Side Effects & Safety Data
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There are 374 adverse event reports in the FDA FAERS database where MELPHALAN was used for Allogenic stem cell transplantation.
Most Reported Side Effects for MELPHALAN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 2,002 | 12.5% | 437 | 495 |
| Febrile neutropenia | 931 | 5.8% | 145 | 419 |
| Drug ineffective | 853 | 5.3% | 199 | 213 |
| Neutropenia | 810 | 5.0% | 145 | 246 |
| Mucosal inflammation | 804 | 5.0% | 131 | 254 |
| Plasma cell myeloma | 781 | 4.9% | 223 | 99 |
| Product use in unapproved indication | 765 | 4.8% | 144 | 182 |
| Thrombocytopenia | 701 | 4.4% | 118 | 253 |
| Diarrhoea | 698 | 4.4% | 95 | 343 |
| Pyrexia | 667 | 4.2% | 144 | 346 |
| Pneumonia | 650 | 4.1% | 254 | 382 |
| Disease progression | 595 | 3.7% | 155 | 90 |
| Myelodysplastic syndrome | 573 | 3.6% | 231 | 132 |
| Sepsis | 544 | 3.4% | 316 | 247 |
| Venoocclusive liver disease | 464 | 2.9% | 152 | 130 |
Other Indications for MELPHALAN
Plasma cell myeloma (4,878)
Bone marrow conditioning regimen (2,368)
Product used for unknown indication (963)
Stem cell transplant (738)
Retinoblastoma (715)
Diffuse large b-cell lymphoma (595)
Neuroblastoma (495)
Hodgkin's disease (351)
Autologous haematopoietic stem cell transplant (284)
Chemotherapy (284)
Other Drugs Used for Allogenic stem cell transplantation
FLUDARABINE (2,008)
BUSULFAN (1,624)
THIOTEPA (1,476)
CYCLOPHOSPHAMIDE (701)
CYCLOSPORINE (556)
LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN (539)
MYCOPHENOLATE MOFETIL (428)
TREOSULFAN (397)
TACROLIMUS (326)
THYMOCYTE IMMUNE GLOBULIN NOS (269)