TRAMETINIB for Malignant melanoma: Side Effects & Safety Data
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There are 1,448 adverse event reports in the FDA FAERS database where TRAMETINIB was used for Malignant melanoma.
Most Reported Side Effects for TRAMETINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Pyrexia | 1,096 | 18.8% | 113 | 640 |
| Malignant neoplasm progression | 807 | 13.8% | 320 | 205 |
| Product use in unapproved indication | 349 | 6.0% | 33 | 36 |
| Diarrhoea | 325 | 5.6% | 42 | 183 |
| Nausea | 301 | 5.2% | 67 | 172 |
| Rash | 290 | 5.0% | 25 | 96 |
| Vomiting | 289 | 5.0% | 59 | 187 |
| Fatigue | 269 | 4.6% | 39 | 127 |
| Death | 240 | 4.1% | 240 | 40 |
| Chills | 227 | 3.9% | 29 | 128 |
| Asthenia | 193 | 3.3% | 42 | 92 |
| Drug ineffective | 192 | 3.3% | 77 | 53 |
| Anaemia | 184 | 3.2% | 32 | 124 |
| Off label use | 176 | 3.0% | 37 | 38 |
| Metastatic malignant melanoma | 173 | 3.0% | 119 | 75 |
Other Indications for TRAMETINIB
Metastatic malignant melanoma (1,604)
Product used for unknown indication (505)
Non-small cell lung cancer (191)
Colorectal cancer (158)
Glioma (139)
Braf gene mutation (94)
Neoplasm (84)
Neoplasm malignant (81)
Braf v600e mutation positive (80)
Ovarian cancer (64)
Other Drugs Used for Malignant melanoma
NIVOLUMAB (10,599)
IPILIMUMAB (8,903)
DABRAFENIB (5,277)
TRAMETINIB DIMETHYL SULFOXIDE (3,841)
PEMBROLIZUMAB (3,261)
BINIMETINIB (2,613)
ENCORAFENIB (2,591)
VEMURAFENIB (2,548)
COBIMETINIB (1,324)
TALIMOGENE LAHERPAREPVEC (562)