BINIMETINIB for Malignant melanoma: Side Effects & Safety Data
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There are 2,613 adverse event reports in the FDA FAERS database where BINIMETINIB was used for Malignant melanoma.
Most Reported Side Effects for BINIMETINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 902 | 13.1% | 150 | 179 |
| Death | 719 | 10.4% | 710 | 47 |
| Nausea | 657 | 9.5% | 33 | 181 |
| Fatigue | 562 | 8.1% | 36 | 144 |
| Diarrhoea | 521 | 7.5% | 31 | 212 |
| Product use in unapproved indication | 508 | 7.4% | 86 | 64 |
| Pyrexia | 490 | 7.1% | 30 | 215 |
| Neoplasm progression | 387 | 5.6% | 122 | 88 |
| Vomiting | 375 | 5.4% | 20 | 145 |
| Rash | 360 | 5.2% | 19 | 80 |
| Serous retinal detachment | 299 | 4.3% | 13 | 56 |
| Arthralgia | 206 | 3.0% | 6 | 38 |
| Malaise | 205 | 3.0% | 20 | 67 |
| Decreased appetite | 198 | 2.9% | 25 | 85 |
| Vision blurred | 197 | 2.9% | 5 | 44 |
Other Indications for BINIMETINIB
Metastatic malignant melanoma (841)
Colon cancer (715)
Product used for unknown indication (235)
Metastasis (172)
Neoplasm malignant (171)
Thyroid cancer (113)
Non-small cell lung cancer (95)
Colorectal cancer metastatic (91)
Colorectal cancer (74)
Lung neoplasm malignant (71)
Other Drugs Used for Malignant melanoma
NIVOLUMAB (10,599)
IPILIMUMAB (8,903)
DABRAFENIB (5,277)
TRAMETINIB DIMETHYL SULFOXIDE (3,841)
PEMBROLIZUMAB (3,261)
ENCORAFENIB (2,591)
VEMURAFENIB (2,548)
TRAMETINIB (1,448)
COBIMETINIB (1,324)
TALIMOGENE LAHERPAREPVEC (562)