Does BINIMETINIB Cause Off label use? 902 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 902 reports of Off label use have been filed in association with BINIMETINIB (MEKTOVI). This represents 13.1% of all adverse event reports for BINIMETINIB.
902
Reports of Off label use with BINIMETINIB
13.1%
of all BINIMETINIB reports
150
Deaths
179
Hospitalizations
How Dangerous Is Off label use From BINIMETINIB?
Of the 902 reports, 150 (16.6%) resulted in death, 179 (19.8%) required hospitalization, and 10 (1.1%) were considered life-threatening.
Is Off label use Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BINIMETINIB. However, 902 reports have been filed with the FAERS database.
What Other Side Effects Does BINIMETINIB Cause?
Death (719)
Nausea (657)
Fatigue (562)
Diarrhoea (521)
Product use in unapproved indication (508)
Pyrexia (490)
Neoplasm progression (387)
Vomiting (375)
Rash (360)
Serous retinal detachment (299)
What Other Drugs Cause Off label use?
RITUXIMAB (39,751)
INFLIXIMAB (34,801)
DENOSUMAB (34,612)
METHOTREXATE (24,020)
VEDOLIZUMAB (21,017)
ETANERCEPT (20,178)
TOCILIZUMAB (18,256)
PREDNISONE (17,867)
LENALIDOMIDE (17,017)
ADALIMUMAB (16,417)
Which BINIMETINIB Alternatives Have Lower Off label use Risk?
BINIMETINIB vs BIOFLAVONOIDS
BINIMETINIB vs BIOTIN
BINIMETINIB vs BIPERIDEN
BINIMETINIB vs BIRCH TRITERPENES
BINIMETINIB vs BISACODYL