BINIMETINIB for Metastasis: Side Effects & Safety Data
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There are 172 adverse event reports in the FDA FAERS database where BINIMETINIB was used for Metastasis.
Most Reported Side Effects for BINIMETINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 902 | 13.1% | 150 | 179 |
| Death | 719 | 10.4% | 710 | 47 |
| Nausea | 657 | 9.5% | 33 | 181 |
| Fatigue | 562 | 8.1% | 36 | 144 |
| Diarrhoea | 521 | 7.5% | 31 | 212 |
| Product use in unapproved indication | 508 | 7.4% | 86 | 64 |
| Pyrexia | 490 | 7.1% | 30 | 215 |
| Neoplasm progression | 387 | 5.6% | 122 | 88 |
| Vomiting | 375 | 5.4% | 20 | 145 |
| Rash | 360 | 5.2% | 19 | 80 |
| Serous retinal detachment | 299 | 4.3% | 13 | 56 |
| Arthralgia | 206 | 3.0% | 6 | 38 |
| Malaise | 205 | 3.0% | 20 | 67 |
| Decreased appetite | 198 | 2.9% | 25 | 85 |
| Vision blurred | 197 | 2.9% | 5 | 44 |
Other Indications for BINIMETINIB
Malignant melanoma (2,613)
Metastatic malignant melanoma (841)
Colon cancer (715)
Product used for unknown indication (235)
Neoplasm malignant (171)
Thyroid cancer (113)
Non-small cell lung cancer (95)
Colorectal cancer metastatic (91)
Colorectal cancer (74)
Lung neoplasm malignant (71)
Other Drugs Used for Metastasis
CABOZANTINIB S-MALATE (225)
ENCORAFENIB (168)
CARBOPLATIN (114)
CAPECITABINE (109)
PACLITAXEL (101)
BEVACIZUMAB (97)
FLUOROURACIL (96)
DABRAFENIB (93)
TRAMETINIB DIMETHYL SULFOXIDE (93)
ETOPOSIDE (87)