Does TRAMETINIB Cause Left ventricular dysfunction? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Left ventricular dysfunction have been filed in association with TRAMETINIB. This represents 0.5% of all adverse event reports for TRAMETINIB.
27
Reports of Left ventricular dysfunction with TRAMETINIB
0.5%
of all TRAMETINIB reports
3
Deaths
11
Hospitalizations
How Dangerous Is Left ventricular dysfunction From TRAMETINIB?
Of the 27 reports, 3 (11.1%) resulted in death, 11 (40.7%) required hospitalization, and 5 (18.5%) were considered life-threatening.
Is Left ventricular dysfunction Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRAMETINIB. However, 27 reports have been filed with the FAERS database.
What Other Side Effects Does TRAMETINIB Cause?
Pyrexia (1,096)
Malignant neoplasm progression (807)
Product use in unapproved indication (349)
Diarrhoea (325)
Nausea (301)
Rash (290)
Vomiting (289)
Fatigue (269)
Death (240)
Chills (227)
What Other Drugs Cause Left ventricular dysfunction?
DOXORUBICIN (430)
CYCLOPHOSPHAMIDE (426)
TRASTUZUMAB (401)
CLOZAPINE (231)
SACUBITRIL\VALSARTAN (231)
BISOPROLOL (225)
PERTUZUMAB (207)
RITUXIMAB (202)
DOCETAXEL (199)
VINCRISTINE (193)
Which TRAMETINIB Alternatives Have Lower Left ventricular dysfunction Risk?
TRAMETINIB vs TRAMETINIB DIMETHYL SULFOXIDE
TRAMETINIB vs TRANDOLAPRIL
TRAMETINIB vs TRANDOLAPRIL\VERAPAMIL
TRAMETINIB vs TRANEXAMIC ACID
TRAMETINIB vs TRANYLCYPROMINE