Does TRAMETINIB Cause Pancytopenia? 32 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 32 reports of Pancytopenia have been filed in association with TRAMETINIB. This represents 0.6% of all adverse event reports for TRAMETINIB.
32
Reports of Pancytopenia with TRAMETINIB
0.6%
of all TRAMETINIB reports
7
Deaths
22
Hospitalizations
How Dangerous Is Pancytopenia From TRAMETINIB?
Of the 32 reports, 7 (21.9%) resulted in death, 22 (68.8%) required hospitalization, and 3 (9.4%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRAMETINIB. However, 32 reports have been filed with the FAERS database.
What Other Side Effects Does TRAMETINIB Cause?
Pyrexia (1,096)
Malignant neoplasm progression (807)
Product use in unapproved indication (349)
Diarrhoea (325)
Nausea (301)
Rash (290)
Vomiting (289)
Fatigue (269)
Death (240)
Chills (227)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which TRAMETINIB Alternatives Have Lower Pancytopenia Risk?
TRAMETINIB vs TRAMETINIB DIMETHYL SULFOXIDE
TRAMETINIB vs TRANDOLAPRIL
TRAMETINIB vs TRANDOLAPRIL\VERAPAMIL
TRAMETINIB vs TRANEXAMIC ACID
TRAMETINIB vs TRANYLCYPROMINE