TRASTUZUMAB for Prophylaxis: Side Effects & Safety Data
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There are 21 adverse event reports in the FDA FAERS database where TRASTUZUMAB was used for Prophylaxis.
Most Reported Side Effects for TRASTUZUMAB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 4,996 | 10.7% | 484 | 2,202 |
| Off label use | 3,802 | 8.2% | 801 | 1,145 |
| Nausea | 3,499 | 7.5% | 402 | 1,460 |
| Fatigue | 3,417 | 7.3% | 444 | 1,306 |
| Myelosuppression | 2,552 | 5.5% | 10 | 1,110 |
| Disease progression | 2,449 | 5.3% | 689 | 462 |
| Death | 2,378 | 5.1% | 2,376 | 236 |
| Vomiting | 2,244 | 4.8% | 265 | 1,146 |
| Dyspnoea | 2,010 | 4.3% | 233 | 1,046 |
| Pyrexia | 1,886 | 4.1% | 192 | 1,067 |
| Asthenia | 1,835 | 3.9% | 300 | 708 |
| Neuropathy peripheral | 1,733 | 3.7% | 228 | 495 |
| Neutropenia | 1,627 | 3.5% | 240 | 530 |
| Ejection fraction decreased | 1,579 | 3.4% | 157 | 417 |
| Alopecia | 1,464 | 3.2% | 170 | 324 |
Other Indications for TRASTUZUMAB
Breast cancer (15,522)
Breast cancer metastatic (6,303)
Product used for unknown indication (5,641)
Her2 positive breast cancer (5,549)
Her-2 positive breast cancer (3,520)
Invasive ductal breast carcinoma (1,576)
Breast cancer female (1,068)
Gastric cancer (917)
Invasive breast carcinoma (489)
Neoplasm malignant (476)
Other Drugs Used for Prophylaxis
PEGFILGRASTIM (7,424)
HUMAN C1-ESTERASE INHIBITOR (5,950)
DENOSUMAB (4,541)
SULFAMETHOXAZOLE\TRIMETHOPRIM (3,197)
ASPIRIN (2,083)
VALACYCLOVIR (1,574)
PANTOPRAZOLE (1,502)
VARICELLA-ZOSTER VIRUS STRAIN OKA/MERCK LIVE ANTIGEN (1,444)
CLOPIDOGREL BISULFATE (1,296)
ENOXAPARIN (1,278)