Does TREOSULFAN Cause Sepsis? 58 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 58 reports of Sepsis have been filed in association with TREOSULFAN (GRAFAPEX). This represents 3.4% of all adverse event reports for TREOSULFAN.
58
Reports of Sepsis with TREOSULFAN
3.4%
of all TREOSULFAN reports
35
Deaths
17
Hospitalizations
How Dangerous Is Sepsis From TREOSULFAN?
Of the 58 reports, 35 (60.3%) resulted in death, 17 (29.3%) required hospitalization, and 7 (12.1%) were considered life-threatening.
Is Sepsis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TREOSULFAN. However, 58 reports have been filed with the FAERS database.
What Other Side Effects Does TREOSULFAN Cause?
Off label use (418)
Cytomegalovirus infection (211)
Mucosal inflammation (199)
Cytomegalovirus infection reactivation (190)
Adenovirus infection (168)
Product use in unapproved indication (161)
Acute graft versus host disease in skin (145)
Drug ineffective (117)
Graft versus host disease in skin (109)
Human herpesvirus 6 infection (104)
What Other Drugs Cause Sepsis?
RITUXIMAB (4,043)
CYCLOPHOSPHAMIDE (4,041)
METHOTREXATE (3,933)
ADALIMUMAB (3,169)
DEXAMETHASONE (3,150)
LENALIDOMIDE (2,956)
VINCRISTINE (2,791)
DOXORUBICIN (2,740)
PREDNISONE (2,634)
PREDNISOLONE (2,281)
Which TREOSULFAN Alternatives Have Lower Sepsis Risk?
TREOSULFAN vs TREPROSTINIL
TREOSULFAN vs TREPROSTINIL DIOLAMINE
TREOSULFAN vs TRETINOIN
TREOSULFAN vs TRIAMCINOLONE
TREOSULFAN vs TRIAMCINOLONE ACETONIDE