Does TRIMETHOPRIM Cause Pemphigus? 16 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 16 reports of Pemphigus have been filed in association with TRIMETHOPRIM (Trimethoprim). This represents 0.5% of all adverse event reports for TRIMETHOPRIM.
16
Reports of Pemphigus with TRIMETHOPRIM
0.5%
of all TRIMETHOPRIM reports
8
Deaths
13
Hospitalizations
How Dangerous Is Pemphigus From TRIMETHOPRIM?
Of the 16 reports, 8 (50.0%) resulted in death, 13 (81.3%) required hospitalization, and 9 (56.3%) were considered life-threatening.
Is Pemphigus Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRIMETHOPRIM. However, 16 reports have been filed with the FAERS database.
What Other Side Effects Does TRIMETHOPRIM Cause?
Headache (409)
Nausea (383)
Off label use (376)
Drug ineffective (368)
Malaise (346)
Swelling face (267)
Hypersensitivity (260)
Acute kidney injury (249)
Rash (235)
Drug intolerance (231)
What Other Drugs Cause Pemphigus?
RITUXIMAB (8,574)
ABATACEPT (8,441)
METHOTREXATE (8,414)
PREDNISONE (8,260)
LEFLUNOMIDE (8,252)
TOCILIZUMAB (8,210)
FOLIC ACID (8,128)
ADALIMUMAB (8,079)
CETIRIZINE (8,063)
HYDROXYCHLOROQUINE (8,051)
Which TRIMETHOPRIM Alternatives Have Lower Pemphigus Risk?
TRIMETHOPRIM vs TRIMIPRAMINE
TRIMETHOPRIM vs TRIPROLIDINE
TRIMETHOPRIM vs TRIPTORELIN
TRIMETHOPRIM vs TRISODIUM
TRIMETHOPRIM vs TROFINETIDE