TUCATINIB for Prophylaxis: Side Effects & Safety Data
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There are 13 adverse event reports in the FDA FAERS database where TUCATINIB was used for Prophylaxis.
Most Reported Side Effects for TUCATINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 1,587 | 26.3% | 73 | 406 |
| Nausea | 862 | 14.3% | 29 | 273 |
| Fatigue | 843 | 14.0% | 49 | 216 |
| Vomiting | 483 | 8.0% | 24 | 204 |
| Death | 400 | 6.6% | 399 | 88 |
| Off label use | 392 | 6.5% | 31 | 112 |
| Malignant neoplasm progression | 361 | 6.0% | 37 | 26 |
| Palmar-plantar erythrodysaesthesia syndrome | 355 | 5.9% | 16 | 49 |
| Product dose omission issue | 332 | 5.5% | 19 | 122 |
| Asthenia | 322 | 5.3% | 34 | 134 |
| Decreased appetite | 286 | 4.7% | 16 | 67 |
| Metastases to central nervous system | 270 | 4.5% | 26 | 61 |
| Disease progression | 268 | 4.4% | 40 | 62 |
| Dehydration | 239 | 4.0% | 9 | 154 |
| Neoplasm progression | 237 | 3.9% | 35 | 37 |
Other Indications for TUCATINIB
Breast cancer female (1,890)
Her2 positive breast cancer (993)
Product used for unknown indication (825)
Breast cancer metastatic (738)
Breast cancer (552)
Metastases to central nervous system (77)
Neoplasm malignant (57)
Colorectal cancer metastatic (52)
Colon cancer (49)
Invasive breast carcinoma (38)
Other Drugs Used for Prophylaxis
PEGFILGRASTIM (7,424)
HUMAN C1-ESTERASE INHIBITOR (5,950)
DENOSUMAB (4,541)
SULFAMETHOXAZOLE\TRIMETHOPRIM (3,197)
ASPIRIN (2,083)
VALACYCLOVIR (1,574)
PANTOPRAZOLE (1,502)
VARICELLA-ZOSTER VIRUS STRAIN OKA/MERCK LIVE ANTIGEN (1,444)
CLOPIDOGREL BISULFATE (1,296)
ENOXAPARIN (1,278)