VALPROATE for Seizure prophylaxis: Side Effects & Safety Data
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There are 178 adverse event reports in the FDA FAERS database where VALPROATE was used for Seizure prophylaxis.
Most Reported Side Effects for VALPROATE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Foetal exposure during pregnancy | 1,982 | 12.5% | 122 | 342 |
| Drug ineffective | 1,268 | 8.0% | 44 | 526 |
| Seizure | 1,083 | 6.8% | 48 | 408 |
| Epilepsy | 878 | 5.5% | 46 | 279 |
| Somnolence | 843 | 5.3% | 35 | 421 |
| Off label use | 744 | 4.7% | 53 | 351 |
| Drug abuse | 705 | 4.4% | 28 | 487 |
| Sopor | 577 | 3.6% | 5 | 415 |
| Dysmorphism | 552 | 3.5% | 20 | 218 |
| Drug interaction | 513 | 3.2% | 46 | 239 |
| Foetal anticonvulsant syndrome | 511 | 3.2% | 8 | 119 |
| Toxicity to various agents | 487 | 3.1% | 88 | 320 |
| Intentional overdose | 486 | 3.1% | 17 | 296 |
| Tremor | 462 | 2.9% | 9 | 217 |
| Disturbance in attention | 460 | 2.9% | 4 | 195 |
Other Indications for VALPROATE
Product used for unknown indication (4,175)
Epilepsy (3,697)
Maternal exposure timing unspecified (1,477)
Bipolar disorder (659)
Seizure (599)
Schizophrenia (413)
Status epilepticus (294)
Generalised tonic-clonic seizure (254)
Partial seizures (238)
Affective disorder (217)
Other Drugs Used for Seizure prophylaxis
LEVETIRACETAM (942)
CARBAMAZEPINE (352)
CYCLOBENZAPRINE (146)
PHENYTOIN (130)
MAGNESIUM (80)
LACOSAMIDE (78)
QUINAPRIL (55)
VALPROIC ACID (54)
LAMOTRIGINE (41)
PHENOBARBITAL (33)