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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Seizure prophylaxis: Which Medications Are Safest? (70 Drugs Compared)

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70 medications are used for Seizure prophylaxis, with 1,958 combined adverse event reports. The most reported drugs for Seizure prophylaxis are LEVETIRACETAM and CARBAMAZEPINE.

1,958
Total Reports
70
Drugs Used

All Medications for Seizure prophylaxis Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
LEVETIRACETAM Levetiracetam 942 4,322 19,165 6.9%
CARBAMAZEPINE Carbamazepine 352 2,156 9,608 8.8%
VALPROATE Valproate Sodium 178 1,000 6,625 6.3%
CYCLOBENZAPRINE Cyclobenzaprine hydrochloride 146 3,862 2,820 42.2%
PHENYTOIN PHENYTOIN SODIUM 130 1,449 5,241 10.0%
MAGNESIUM citroma 80 1,878 4,530 19.3%
LACOSAMIDE Lacosamide 78 1,987 6,845 9.4%
QUINAPRIL Quinapril 55 51 830 2.8%
VALPROIC ACID Valproic Acid 54 2,667 8,183 13.3%
LAMOTRIGINE Lamotrigine ER 41 6,604 17,639 13.7%
PHENOBARBITAL Phenobarbital Sodium 33 945 2,668 14.6%
DIVALPROEX Divalproex Sodium 24 478 4,169 4.2%
MAGNESIUM\MAGNESIUM HEPTAHYDRATE - 24 18 208 3.8%
CLOBAZAM Clobazam 18 725 3,312 6.8%
OXCARBAZEPINE OXCARBAZEPINE 17 864 3,159 8.0%
TOPIRAMATE Topiramate 15 3,527 7,098 12.3%
DIAZEPAM Diazepam 13 12,045 13,635 31.6%
CLONAZEPAM Clonazepam 12 8,488 12,506 21.5%
GABAPENTIN Gabapentin 11 11,101 16,499 14.9%
METHYLPREDNISOLONE Medroloan II SUIK 11 12,828 26,552 20.1%

View all 70 drugs →

Most Reported Drugs for Seizure prophylaxis

#1 most reported
#2 most reported
#3 most reported