Does VALPROATE Cause Hypertonia? 84 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 84 reports of Hypertonia have been filed in association with VALPROATE (Valproate Sodium). This represents 0.5% of all adverse event reports for VALPROATE.
84
Reports of Hypertonia with VALPROATE
0.5%
of all VALPROATE reports
6
Deaths
34
Hospitalizations
How Dangerous Is Hypertonia From VALPROATE?
Of the 84 reports, 6 (7.1%) resulted in death, 34 (40.5%) required hospitalization, and 7 (8.3%) were considered life-threatening.
Is Hypertonia Listed in the Official Label?
Yes, Hypertonia is listed as a known adverse reaction in the official FDA drug label for VALPROATE.
What Other Side Effects Does VALPROATE Cause?
Foetal exposure during pregnancy (1,982)
Drug ineffective (1,268)
Seizure (1,083)
Epilepsy (878)
Somnolence (843)
Off label use (744)
Drug abuse (705)
Sopor (577)
Dysmorphism (552)
Drug interaction (513)
What Other Drugs Cause Hypertonia?
BACLOFEN (479)
QUETIAPINE (132)
RISPERIDONE (126)
OLANZAPINE (118)
ARIPIPRAZOLE (108)
SERTRALINE (108)
ACETAMINOPHEN (99)
HALOPERIDOL (99)
CLONAZEPAM (84)
ESCITALOPRAM OXALATE (78)
Which VALPROATE Alternatives Have Lower Hypertonia Risk?
VALPROATE vs VALPROIC ACID
VALPROATE vs VALPROMIDE
VALPROATE vs VALSARTAN
VALPROATE vs VALTREX
VALPROATE vs VAMOROLONE