Hypertonia: Which Medications Cause It? (2,682 Reports Across 278 Drugs)
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Hypertonia has been reported as an adverse event with 278 different drugs in the FDA's FAERS database, with 2,682 total reports. 110 of these reports resulted in death.The drugs most commonly associated with Hypertonia are BACLOFEN, QUETIAPINE, and RISPERIDONE.
2,682
Total Reports
278
Drugs Involved
110
Deaths
1,546
Hospitalizations
40.9 yrs
Average Patient Age
48.9% / 51.1%
Female / Male
Which Drugs Cause Hypertonia Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| BACLOFEN | 479 | 1.9% | 11 | 205 | 18 |
| QUETIAPINE | 132 | 0.2% | 4 | 98 | 44 |
| RISPERIDONE | 126 | 0.2% | 2 | 87 | 23 |
| OLANZAPINE | 118 | 0.2% | 6 | 80 | 18 |
| ARIPIPRAZOLE | 108 | 0.2% | 1 | 87 | 13 |
| SERTRALINE | 108 | 0.2% | 5 | 65 | 17 |
| ACETAMINOPHEN | 99 | 0.1% | 8 | 82 | 41 |
| HALOPERIDOL | 99 | 0.6% | 4 | 66 | 5 |
| CLONAZEPAM | 84 | 0.2% | 5 | 43 | 6 |
| VALPROATE | 84 | 0.5% | 6 | 34 | 7 |
| ESCITALOPRAM OXALATE | 78 | 0.3% | 12 | 49 | 7 |
| VENLAFAXINE | 78 | 0.2% | 0 | 53 | 21 |
| PAROXETINE | 73 | 0.3% | 1 | 58 | 12 |
| TRAMADOL | 73 | 0.1% | 14 | 49 | 1 |
| LAMOTRIGINE | 68 | 0.1% | 2 | 48 | 11 |
| LORAZEPAM | 67 | 0.2% | 5 | 59 | 21 |
| FLUOXETINE | 62 | 0.2% | 1 | 48 | 4 |
| AMITRIPTYLINE | 59 | 0.3% | 0 | 21 | 6 |
| DULOXETINE | 57 | 0.1% | 1 | 35 | 14 |
| ONDANSETRON | 57 | 0.3% | 0 | 42 | 15 |