Does VALPROIC ACID Cause Cardiomegaly? 45 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 45 reports of Cardiomegaly have been filed in association with VALPROIC ACID (Valproic Acid). This represents 0.2% of all adverse event reports for VALPROIC ACID.
45
Reports of Cardiomegaly with VALPROIC ACID
0.2%
of all VALPROIC ACID reports
4
Deaths
21
Hospitalizations
How Dangerous Is Cardiomegaly From VALPROIC ACID?
Of the 45 reports, 4 (8.9%) resulted in death, 21 (46.7%) required hospitalization, and 7 (15.6%) were considered life-threatening.
Is Cardiomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROIC ACID. However, 45 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROIC ACID Cause?
Drug ineffective (3,511)
Drug interaction (1,542)
Toxicity to various agents (1,517)
Off label use (1,503)
Seizure (1,335)
Foetal exposure during pregnancy (1,046)
Somnolence (831)
Completed suicide (723)
Overdose (691)
Condition aggravated (673)
What Other Drugs Cause Cardiomegaly?
SACUBITRIL\VALSARTAN (365)
ADALIMUMAB (301)
ONDANSETRON (198)
OXYCODONE (164)
AMLODIPINE (161)
CARVEDILOL (151)
MACITENTAN (141)
ACETAMINOPHEN (133)
TREPROSTINIL (129)
FUROSEMIDE (122)
Which VALPROIC ACID Alternatives Have Lower Cardiomegaly Risk?
VALPROIC ACID vs VALPROMIDE
VALPROIC ACID vs VALSARTAN
VALPROIC ACID vs VALTREX
VALPROIC ACID vs VAMOROLONE
VALPROIC ACID vs VANCOMYCIN