Does VALPROIC ACID Cause Hyponatraemia? 190 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 190 reports of Hyponatraemia have been filed in association with VALPROIC ACID (Valproic Acid). This represents 1.0% of all adverse event reports for VALPROIC ACID.
190
Reports of Hyponatraemia with VALPROIC ACID
1.0%
of all VALPROIC ACID reports
11
Deaths
127
Hospitalizations
How Dangerous Is Hyponatraemia From VALPROIC ACID?
Of the 190 reports, 11 (5.8%) resulted in death, 127 (66.8%) required hospitalization, and 20 (10.5%) were considered life-threatening.
Is Hyponatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROIC ACID. However, 190 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROIC ACID Cause?
Drug ineffective (3,511)
Drug interaction (1,542)
Toxicity to various agents (1,517)
Off label use (1,503)
Seizure (1,335)
Foetal exposure during pregnancy (1,046)
Somnolence (831)
Completed suicide (723)
Overdose (691)
Condition aggravated (673)
What Other Drugs Cause Hyponatraemia?
FUROSEMIDE (3,127)
HYDROCHLOROTHIAZIDE (2,138)
OMEPRAZOLE (1,635)
LANSOPRAZOLE (1,416)
SERTRALINE (1,332)
RAMIPRIL (1,178)
SPIRONOLACTONE (1,166)
PANTOPRAZOLE (1,134)
INDAPAMIDE (976)
AMLODIPINE (879)
Which VALPROIC ACID Alternatives Have Lower Hyponatraemia Risk?
VALPROIC ACID vs VALPROMIDE
VALPROIC ACID vs VALSARTAN
VALPROIC ACID vs VALTREX
VALPROIC ACID vs VAMOROLONE
VALPROIC ACID vs VANCOMYCIN