Does VALPROIC ACID Cause Lactic acidosis? 60 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 60 reports of Lactic acidosis have been filed in association with VALPROIC ACID (Valproic Acid). This represents 0.3% of all adverse event reports for VALPROIC ACID.
60
Reports of Lactic acidosis with VALPROIC ACID
0.3%
of all VALPROIC ACID reports
15
Deaths
50
Hospitalizations
How Dangerous Is Lactic acidosis From VALPROIC ACID?
Of the 60 reports, 15 (25.0%) resulted in death, 50 (83.3%) required hospitalization, and 13 (21.7%) were considered life-threatening.
Is Lactic acidosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROIC ACID. However, 60 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROIC ACID Cause?
Drug ineffective (3,511)
Drug interaction (1,542)
Toxicity to various agents (1,517)
Off label use (1,503)
Seizure (1,335)
Foetal exposure during pregnancy (1,046)
Somnolence (831)
Completed suicide (723)
Overdose (691)
Condition aggravated (673)
What Other Drugs Cause Lactic acidosis?
METFORMIN (16,316)
AMLODIPINE (886)
LINEZOLID (824)
FUROSEMIDE (698)
ACETAMINOPHEN (561)
METFORMIN\SITAGLIPTIN (557)
ALBUTEROL (467)
EMPAGLIFLOZIN (434)
RAMIPRIL (430)
BISOPROLOL (425)
Which VALPROIC ACID Alternatives Have Lower Lactic acidosis Risk?
VALPROIC ACID vs VALPROMIDE
VALPROIC ACID vs VALSARTAN
VALPROIC ACID vs VALTREX
VALPROIC ACID vs VAMOROLONE
VALPROIC ACID vs VANCOMYCIN