Does VALPROIC ACID Cause Pyroglutamic acidosis? 13 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 13 reports of Pyroglutamic acidosis have been filed in association with VALPROIC ACID (Valproic Acid). This represents 0.1% of all adverse event reports for VALPROIC ACID.
13
Reports of Pyroglutamic acidosis with VALPROIC ACID
0.1%
of all VALPROIC ACID reports
0
Deaths
11
Hospitalizations
How Dangerous Is Pyroglutamic acidosis From VALPROIC ACID?
Of the 13 reports, 11 (84.6%) required hospitalization.
Is Pyroglutamic acidosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROIC ACID. However, 13 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROIC ACID Cause?
Drug ineffective (3,511)
Drug interaction (1,542)
Toxicity to various agents (1,517)
Off label use (1,503)
Seizure (1,335)
Foetal exposure during pregnancy (1,046)
Somnolence (831)
Completed suicide (723)
Overdose (691)
Condition aggravated (673)
What Other Drugs Cause Pyroglutamic acidosis?
ACETAMINOPHEN (305)
FLUCLOXACILLIN (83)
ACETAMINOPHEN\HYDROCODONE (30)
IBUPROFEN (18)
CEFUROXIME (11)
ACETAMINOPHEN\CODEINE (8)
ADALIMUMAB (8)
ACETAMINOPHEN\CODEINE\DOXYLAMINE (7)
ALBUTEROL (7)
PIPERACILLIN (7)
Which VALPROIC ACID Alternatives Have Lower Pyroglutamic acidosis Risk?
VALPROIC ACID vs VALPROMIDE
VALPROIC ACID vs VALSARTAN
VALPROIC ACID vs VALTREX
VALPROIC ACID vs VAMOROLONE
VALPROIC ACID vs VANCOMYCIN