Does VALPROIC ACID Cause Torsade de pointes? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Torsade de pointes have been filed in association with VALPROIC ACID (Valproic Acid). This represents 0.1% of all adverse event reports for VALPROIC ACID.
15
Reports of Torsade de pointes with VALPROIC ACID
0.1%
of all VALPROIC ACID reports
2
Deaths
12
Hospitalizations
How Dangerous Is Torsade de pointes From VALPROIC ACID?
Of the 15 reports, 2 (13.3%) resulted in death, 12 (80.0%) required hospitalization, and 5 (33.3%) were considered life-threatening.
Is Torsade de pointes Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROIC ACID. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROIC ACID Cause?
Drug ineffective (3,511)
Drug interaction (1,542)
Toxicity to various agents (1,517)
Off label use (1,503)
Seizure (1,335)
Foetal exposure during pregnancy (1,046)
Somnolence (831)
Completed suicide (723)
Overdose (691)
Condition aggravated (673)
What Other Drugs Cause Torsade de pointes?
AMIODARONE (522)
LOPERAMIDE (366)
ONDANSETRON (331)
FUROSEMIDE (305)
METHADONE (240)
CITALOPRAM HYDROBROMIDE (182)
QUETIAPINE (172)
OLANZAPINE (171)
HYDROXYCHLOROQUINE (167)
FLUOXETINE (164)
Which VALPROIC ACID Alternatives Have Lower Torsade de pointes Risk?
VALPROIC ACID vs VALPROMIDE
VALPROIC ACID vs VALSARTAN
VALPROIC ACID vs VALTREX
VALPROIC ACID vs VAMOROLONE
VALPROIC ACID vs VANCOMYCIN