VANCOMYCIN for Clostridium difficile infection: Side Effects & Safety Data
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There are 1,214 adverse event reports in the FDA FAERS database where VANCOMYCIN was used for Clostridium difficile infection.
Most Reported Side Effects for VANCOMYCIN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Drug ineffective | 4,938 | 14.6% | 1,672 | 2,641 |
| Acute kidney injury | 4,018 | 11.9% | 469 | 2,563 |
| Drug reaction with eosinophilia and systemic symptoms | 2,509 | 7.4% | 180 | 1,465 |
| Off label use | 2,070 | 6.1% | 506 | 1,095 |
| Drug hypersensitivity | 2,046 | 6.0% | 19 | 400 |
| Pyrexia | 1,596 | 4.7% | 212 | 1,011 |
| Rash | 1,461 | 4.3% | 64 | 665 |
| Condition aggravated | 1,189 | 3.5% | 333 | 629 |
| Pruritus | 958 | 2.8% | 41 | 363 |
| Septic shock | 766 | 2.3% | 508 | 524 |
| Hypotension | 758 | 2.2% | 140 | 485 |
| Clostridium difficile infection | 743 | 2.2% | 107 | 401 |
| Diarrhoea | 739 | 2.2% | 140 | 409 |
| Treatment failure | 733 | 2.2% | 205 | 293 |
| Multiple organ dysfunction syndrome | 728 | 2.2% | 553 | 463 |
Other Indications for VANCOMYCIN
Product used for unknown indication (5,649)
Staphylococcal infection (2,232)
Antibiotic therapy (1,829)
Infection (1,273)
Evidence based treatment (1,240)
Pneumonia (1,137)
Sepsis (1,032)
Osteomyelitis (980)
Endocarditis (733)
Antibiotic prophylaxis (669)
Other Drugs Used for Clostridium difficile infection
METRONIDAZOLE (784)
FIDAXOMICIN (744)
DONOR HUMAN STOOL SPORES (601)
BEZLOTOXUMAB (193)
METRONIDAZOLE\METRONIDAZOLE (136)
DONOR HUMAN STOOL (78)
TIGECYCLINE (37)
RIFAXIMIN (35)
MEROPENEM (30)
FECAL MICROBIOTA (27)