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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Clostridium difficile infection: Which Medications Are Safest? (112 Drugs Compared)

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112 medications are used for Clostridium difficile infection, with 3,292 combined adverse event reports. The most reported drugs for Clostridium difficile infection are VANCOMYCIN and METRONIDAZOLE.

3,292
Total Reports
112
Drugs Used

All Medications for Clostridium difficile infection Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
VANCOMYCIN Vancomycin Hydrochloride 1,214 5,348 15,776 15.8%
METRONIDAZOLE metronidazole 784 2,188 7,909 9.7%
FIDAXOMICIN Dificid 744 181 410 12.1%
DONOR HUMAN STOOL SPORES VOWST 601 11 61 1.6%
BEZLOTOXUMAB ZINPLAVA 193 59 88 19.0%
METRONIDAZOLE\METRONIDAZOLE - 136 158 1,351 3.7%
DONOR HUMAN STOOL Rebyota 78 5 18 2.4%
TIGECYCLINE Tigecycline 37 872 1,283 26.9%
RIFAXIMIN XIFAXAN 35 5,009 4,847 36.1%
MEROPENEM Meropenem 30 3,880 7,167 28.0%
FECAL MICROBIOTA - 27 12 15 24.5%
CEFTRIAXONE Ceftriaxone 23 2,926 9,596 15.1%
PIPERACILLIN\TAZOBACTAM - 22 3,372 10,462 17.6%
HUMAN IMMUNOGLOBULIN G BIVIGAM 18 5,286 16,081 7.5%
CIPROFLOXACIN Ciprofloxacin 16 2,671 13,894 6.1%
CLINDAMYCIN XACIATO 15 986 5,320 5.8%
FLUCLOXACILLIN - 15 187 797 12.5%
PENICILLIN V Penicillin V Potassium 14 178 729 5.8%
LEVOFLOXACIN Levofloxacin 13 2,747 13,832 6.8%
PREDNISONE prednisone 12 22,555 57,772 14.2%

View all 112 drugs →

Most Reported Drugs for Clostridium difficile infection

#1 most reported
#2 most reported
#3 most reported