VORINOSTAT for Diffuse large b-cell lymphoma: Side Effects & Safety Data
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There are 15 adverse event reports in the FDA FAERS database where VORINOSTAT was used for Diffuse large b-cell lymphoma.
Most Reported Side Effects for VORINOSTAT
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Febrile neutropenia | 177 | 14.2% | 25 | 84 |
| Product use in unapproved indication | 122 | 9.8% | 16 | 4 |
| Thrombocytopenia | 89 | 7.1% | 16 | 13 |
| Off label use | 88 | 7.1% | 18 | 28 |
| Anaemia | 79 | 6.3% | 15 | 28 |
| Sepsis | 77 | 6.2% | 28 | 40 |
| Diarrhoea | 68 | 5.5% | 10 | 30 |
| Neutropenia | 63 | 5.1% | 5 | 12 |
| Nausea | 61 | 4.9% | 14 | 29 |
| Fatigue | 59 | 4.7% | 13 | 19 |
| Product use issue | 55 | 4.4% | 6 | 3 |
| Platelet count decreased | 51 | 4.1% | 16 | 35 |
| Vomiting | 50 | 4.0% | 10 | 28 |
| Pneumonia | 47 | 3.8% | 19 | 27 |
| Death | 46 | 3.7% | 46 | 12 |
Other Indications for VORINOSTAT
Acute myeloid leukaemia (253)
Plasma cell myeloma (93)
Mycosis fungoides (82)
Myelodysplastic syndrome (81)
Acute lymphocytic leukaemia (69)
Product used for unknown indication (52)
Cutaneous t-cell lymphoma (38)
Peripheral t-cell lymphoma unspecified (34)
Ewing's sarcoma (26)
Neoplasm malignant (21)
Other Drugs Used for Diffuse large b-cell lymphoma
RITUXIMAB (22,275)
CYCLOPHOSPHAMIDE (16,598)
DOXORUBICIN (15,213)
VINCRISTINE (14,922)
PREDNISONE (11,266)
LENALIDOMIDE (7,858)
ETOPOSIDE (4,698)
PREDNISOLONE (4,086)
CYTARABINE (3,857)
DEXAMETHASONE (3,696)