Does VORINOSTAT Cause Hypocalcaemia? 14 Reports in FDA Database

Q: Does VORINOSTAT cause Hypocalcaemia?

14 reports of Hypocalcaemia have been filed with the FDA for VORINOSTAT, representing 1.1% of all VORINOSTAT adverse event reports.

Q: How dangerous is Hypocalcaemia from VORINOSTAT?

Of 14 reports, 7 (50.0%) resulted in death and 5 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 14 reports of Hypocalcaemia have been filed in association with VORINOSTAT (ZOLINZA). This represents 1.1% of all adverse event reports for VORINOSTAT.

Reports of Hypocalcaemia with VORINOSTAT

1.1%

of all VORINOSTAT reports

Deaths

Hospitalizations

How Dangerous Is Hypocalcaemia From VORINOSTAT?

Of the 14 reports, 7 (50.0%) resulted in death, 5 (35.7%) required hospitalization, and 2 (14.3%) were considered life-threatening.

Is Hypocalcaemia Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for VORINOSTAT. However, 14 reports have been filed with the FAERS database.

What Other Side Effects Does VORINOSTAT Cause?

Febrile neutropenia (177) Product use in unapproved indication (122) Thrombocytopenia (89) Off label use (88) Anaemia (79) Sepsis (77) Diarrhoea (68) Neutropenia (63) Nausea (61) Fatigue (59)

What Other Drugs Cause Hypocalcaemia?

DENOSUMAB (2,345) OMEPRAZOLE (966) PANTOPRAZOLE (935) PARATHYROID HORMONE (784) ZOLEDRONIC ACID (513) CINACALCET (468) ESOMEPRAZOLE (451) FUROSEMIDE (429) DEXAMETHASONE (368) PREDNISONE (352)

Which VORINOSTAT Alternatives Have Lower Hypocalcaemia Risk?

VORINOSTAT vs VORTIOXETINE VORINOSTAT vs VORTIOXETINE HYDROBROMIDE VORINOSTAT vs VOSORITIDE VORINOSTAT vs VOTRIENT VORINOSTAT vs VOXELOTOR

VORINOSTAT Full Profile All Hypocalcaemia Reports All Drugs Causing Hypocalcaemia VORINOSTAT Demographics