Does VORINOSTAT Cause Hyponatraemia? 19 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 19 reports of Hyponatraemia have been filed in association with VORINOSTAT (ZOLINZA). This represents 1.5% of all adverse event reports for VORINOSTAT.
19
Reports of Hyponatraemia with VORINOSTAT
1.5%
of all VORINOSTAT reports
4
Deaths
11
Hospitalizations
How Dangerous Is Hyponatraemia From VORINOSTAT?
Of the 19 reports, 4 (21.1%) resulted in death, 11 (57.9%) required hospitalization, and 3 (15.8%) were considered life-threatening.
Is Hyponatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VORINOSTAT. However, 19 reports have been filed with the FAERS database.
What Other Side Effects Does VORINOSTAT Cause?
Febrile neutropenia (177)
Product use in unapproved indication (122)
Thrombocytopenia (89)
Off label use (88)
Anaemia (79)
Sepsis (77)
Diarrhoea (68)
Neutropenia (63)
Nausea (61)
Fatigue (59)
What Other Drugs Cause Hyponatraemia?
FUROSEMIDE (3,127)
HYDROCHLOROTHIAZIDE (2,138)
OMEPRAZOLE (1,635)
LANSOPRAZOLE (1,416)
SERTRALINE (1,332)
RAMIPRIL (1,178)
SPIRONOLACTONE (1,166)
PANTOPRAZOLE (1,134)
INDAPAMIDE (976)
AMLODIPINE (879)
Which VORINOSTAT Alternatives Have Lower Hyponatraemia Risk?
VORINOSTAT vs VORTIOXETINE
VORINOSTAT vs VORTIOXETINE HYDROBROMIDE
VORINOSTAT vs VOSORITIDE
VORINOSTAT vs VOTRIENT
VORINOSTAT vs VOXELOTOR