VOXELOTOR for Sickle cell disease: Side Effects & Safety Data
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There are 14,138 adverse event reports in the FDA FAERS database where VOXELOTOR was used for Sickle cell disease.
Most Reported Side Effects for VOXELOTOR
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Sickle cell anaemia with crisis | 11,023 | 50.2% | 38 | 6,090 |
| Product dose omission issue | 5,122 | 23.4% | 10 | 2,362 |
| Diarrhoea | 3,173 | 14.5% | 6 | 551 |
| Off label use | 2,364 | 10.8% | 27 | 724 |
| Nausea | 2,003 | 9.1% | 6 | 428 |
| Headache | 1,683 | 7.7% | 4 | 307 |
| Abdominal pain upper | 1,165 | 5.3% | 4 | 245 |
| Pain | 1,059 | 4.8% | 10 | 371 |
| Therapy cessation | 1,038 | 4.7% | 5 | 309 |
| Fatigue | 1,004 | 4.6% | 5 | 226 |
| Abdominal discomfort | 961 | 4.4% | 1 | 195 |
| Therapy interrupted | 882 | 4.0% | 1 | 416 |
| Vomiting | 828 | 3.8% | 0 | 210 |
| Haemoglobin decreased | 743 | 3.4% | 3 | 357 |
| Abdominal pain | 625 | 2.9% | 2 | 124 |
Other Indications for VOXELOTOR
Product used for unknown indication (4,689)
Sickle cell anaemia with crisis (1,278)
Sickle cell anaemia (394)
Thalassaemia sickle cell (250)
Haemoglobin c disease (195)
Anaemia (135)
Haemolytic anaemia (87)
Thalassaemia beta (59)
Haemochromatosis (42)
Acute chest syndrome (23)
Other Drugs Used for Sickle cell disease
GLUTAMINE (2,538)
DEFERIPRONE (574)
CRIZANLIZUMAB-TMCA (556)
DEFERASIROX (306)
HYDROXYUREA (246)
CRIZANLIZUMAB (72)
ALEMTUZUMAB (51)
FLUDARABINE (47)
THIOTEPA (43)
CYCLOPHOSPHAMIDE (37)