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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Sickle cell disease: Which Medications Are Safest? (104 Drugs Compared)

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104 medications are used for Sickle cell disease, with 18,624 combined adverse event reports. The most reported drugs for Sickle cell disease are VOXELOTOR and GLUTAMINE.

18,624
Total Reports
104
Drugs Used

All Medications for Sickle cell disease Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
VOXELOTOR OXBRYTA 14,138 396 7,660 1.8%
GLUTAMINE Endari 2,538 31 1,324 0.9%
DEFERIPRONE FERRIPROX 574 287 923 11.5%
CRIZANLIZUMAB-TMCA - 556 37 435 3.3%
DEFERASIROX Deferasirox 306 2,661 4,008 23.5%
HYDROXYUREA Hydroxyurea 246 664 2,103 11.1%
CRIZANLIZUMAB ADAKVEO 72 16 65 12.7%
ALEMTUZUMAB Campath 51 1,417 4,455 10.0%
FLUDARABINE Fludarabine Phosphate 47 6,831 6,745 28.9%
THIOTEPA Thiotepa 43 1,867 1,184 27.3%
CYCLOPHOSPHAMIDE Cyclophosphamide 37 25,330 45,054 19.7%
TREOSULFAN GRAFAPEX 36 322 279 18.8%
BUPRENORPHINE Buprenorphine and Naloxone 19 25,813 9,467 31.5%
BUSULFAN Busulfan 18 3,122 2,271 27.7%
HYDROMORPHONE Hydromorphone Hydrochloride 17 28,491 10,395 34.1%
ECULIZUMAB SOLIRIS 14 4,626 12,421 10.5%
RITUXIMAB Rituxan 14 28,910 54,631 16.2%
ACETAMINOPHEN Hydrocodone Bitartrate and Acetaminophen 12 30,085 50,046 22.0%
ERYTHROPOIETIN - 11 1,199 1,736 15.1%
DEFEROXAMINE Desferal 10 152 314 18.1%

View all 104 drugs →

Most Reported Drugs for Sickle cell disease

#1 most reported
#2 most reported
#3 most reported