XGEVA for Metastases to bone: Side Effects & Safety Data
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There are 412 adverse event reports in the FDA FAERS database where XGEVA was used for Metastases to bone.
Most Reported Side Effects for XGEVA
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 309 | 29.7% | 309 | 24 |
| Osteonecrosis of jaw | 159 | 15.3% | 5 | 14 |
| Investigation | 115 | 11.0% | 11 | 115 |
| Hospitalisation | 77 | 7.4% | 4 | 77 |
| Hypocalcaemia | 48 | 4.6% | 7 | 34 |
| Metastases to bone | 30 | 2.9% | 3 | 2 |
| Pain | 28 | 2.7% | 2 | 9 |
| Pain in extremity | 17 | 1.6% | 1 | 5 |
| Dyspnoea | 16 | 1.5% | 5 | 9 |
| Disease progression | 15 | 1.4% | 6 | 4 |
| Terminal state | 14 | 1.3% | 0 | 2 |
| Back pain | 13 | 1.3% | 0 | 2 |
| Fatigue | 13 | 1.3% | 1 | 4 |
| Hypoaesthesia | 13 | 1.3% | 5 | 6 |
| Malaise | 13 | 1.3% | 2 | 6 |
Other Indications for XGEVA
Prophylaxis (385)
Product used for unknown indication (349)
Prostate cancer (32)
Prostate cancer metastatic (25)
Breast cancer metastatic (24)
Breast cancer (23)
Bone disorder (7)
Osteoporosis (6)
Neoplasm malignant (5)
Other Drugs Used for Metastases to bone
DENOSUMAB (5,083)
ZOLEDRONIC ACID (3,177)
RADIUM RA-223 DICHLORIDE (1,501)
PALBOCICLIB (556)
CABOZANTINIB S-MALATE (514)
ENZALUTAMIDE (439)
RIBOCICLIB (383)
LETROZOLE (263)
CARBOPLATIN (254)
PACLITAXEL (254)