ZOLEDRONIC ACID for Off label use: Side Effects & Safety Data
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There are 47 adverse event reports in the FDA FAERS database where ZOLEDRONIC ACID was used for Off label use.
Most Reported Side Effects for ZOLEDRONIC ACID
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Osteonecrosis of jaw | 5,500 | 16.4% | 216 | 1,278 |
| Death | 3,053 | 9.1% | 3,046 | 212 |
| Pain | 2,925 | 8.7% | 143 | 781 |
| Arthralgia | 2,541 | 7.6% | 262 | 543 |
| Pyrexia | 2,455 | 7.3% | 305 | 952 |
| Fatigue | 2,219 | 6.6% | 322 | 487 |
| Nausea | 1,962 | 5.8% | 286 | 596 |
| Malaise | 1,834 | 5.5% | 310 | 586 |
| Headache | 1,739 | 5.2% | 235 | 376 |
| Asthenia | 1,582 | 4.7% | 332 | 461 |
| Vomiting | 1,538 | 4.6% | 279 | 612 |
| Diarrhoea | 1,530 | 4.6% | 306 | 458 |
| Fall | 1,492 | 4.4% | 310 | 487 |
| Pain in extremity | 1,490 | 4.4% | 54 | 363 |
| Bone pain | 1,364 | 4.1% | 67 | 299 |
Other Indications for ZOLEDRONIC ACID
Osteoporosis (9,860)
Product used for unknown indication (9,388)
Metastases to bone (3,177)
Breast cancer (1,554)
Plasma cell myeloma (1,406)
Breast cancer metastatic (1,225)
Prostate cancer (555)
Hypercalcaemia (413)
Prostate cancer metastatic (410)
Osteopenia (378)
Other Drugs Used for Off label use
LENALIDOMIDE (5,767)
ECULIZUMAB (3,550)
CERTOLIZUMAB PEGOL (2,256)
ABOBOTULINUMTOXINA (2,170)
LEVETIRACETAM (2,161)
APREMILAST (1,995)
PROPRANOLOL (1,576)
CETIRIZINE (1,416)
HUMAN IMMUNOGLOBULIN G (1,129)
THALIDOMIDE (1,033)