Skip to content
Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Bipolar disorder: Which Medications Are Safest? (492 Drugs Compared)

Sharpen Your Memory & Focus Naturally

NeuroZoom — 35 clinically studied ingredients. No stimulants. Pure brain support.

Boost Your Brain

492 medications are used for Bipolar disorder, with 42,608 combined adverse event reports. The most reported drugs for Bipolar disorder are RISPERIDONE and ARIPIPRAZOLE.

42,608
Total Reports
492
Drugs Used

All Medications for Bipolar disorder Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
RISPERIDONE Risperidone 6,866 4,120 18,771 5.2%
ARIPIPRAZOLE Aripiprazole 6,430 3,863 20,713 5.8%
QUETIAPINE Quetiapine 5,449 13,610 31,386 18.6%
LAMOTRIGINE Lamotrigine ER 4,258 6,604 17,639 13.7%
LURASIDONE lurasidone hydrochloride 3,459 709 2,381 4.1%
LITHIUM Bestmade Natural Products Lithium Chloride (Lith Mur) 3,455 1,568 7,711 10.5%
OLANZAPINE Olanzapine 2,942 5,535 21,934 10.8%
LUMATEPERONE CAPLYTA 2,246 41 397 0.8%
PALIPERIDONE paliperidone 1,615 1,809 8,499 4.4%
DIVALPROEX Divalproex Sodium 1,282 478 4,169 4.2%
VALPROIC ACID Valproic Acid 1,137 2,667 8,183 13.3%
CARIPRAZINE Vraylar 1,094 194 702 3.0%
SERTRALINE Sertraline Hydrochloride 947 6,889 19,327 11.5%
CLOZAPINE CLOZAPINE 797 15,347 41,887 16.1%
VENLAFAXINE Venlafaxine Hydrochloride 757 7,521 15,749 15.7%
BUPROPION Bupropion Hydrochloride (XL) 702 8,577 10,246 24.1%
BREXPIPRAZOLE Rexulti 697 673 1,269 5.1%
CLONAZEPAM Clonazepam 665 8,488 12,506 21.5%
VALPROATE Valproate Sodium 659 1,000 6,625 6.3%
CARBAMAZEPINE Carbamazepine 497 2,156 9,608 8.8%

View all 492 drugs →

Most Reported Drugs for Bipolar disorder

#1 most reported
#2 most reported
#3 most reported