VALPROIC ACID for Bipolar disorder: Side Effects & Safety Data

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There are 1,137 adverse event reports in the FDA FAERS database where VALPROIC ACID was used for Bipolar disorder.

Most Reported Side Effects for VALPROIC ACID

Side Effect	Reports	%	Deaths	Hosp.
Drug ineffective	3,511	17.5%	206	1,394
Drug interaction	1,542	7.7%	192	632
Toxicity to various agents	1,517	7.6%	571	941
Off label use	1,503	7.5%	138	595
Seizure	1,335	6.7%	97	487
Foetal exposure during pregnancy	1,046	5.2%	72	115
Somnolence	831	4.2%	33	497
Completed suicide	723	3.6%	721	218
Overdose	691	3.5%	83	516
Condition aggravated	673	3.4%	33	288
Depression	657	3.3%	128	168
Product use in unapproved indication	625	3.1%	69	276
Multiple-drug resistance	622	3.1%	82	135
Status epilepticus	587	2.9%	91	301
Hyperammonaemia	581	2.9%	26	385