Does VALPROIC ACID Cause Depression? 657 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 657 reports of Depression have been filed in association with VALPROIC ACID (Valproic Acid). This represents 3.3% of all adverse event reports for VALPROIC ACID.
657
Reports of Depression with VALPROIC ACID
3.3%
of all VALPROIC ACID reports
128
Deaths
168
Hospitalizations
How Dangerous Is Depression From VALPROIC ACID?
Of the 657 reports, 128 (19.5%) resulted in death, 168 (25.6%) required hospitalization, and 27 (4.1%) were considered life-threatening.
Is Depression Listed in the Official Label?
Yes, Depression is listed as a known adverse reaction in the official FDA drug label for VALPROIC ACID.
What Other Side Effects Does VALPROIC ACID Cause?
Drug ineffective (3,511)
Drug interaction (1,542)
Toxicity to various agents (1,517)
Off label use (1,503)
Seizure (1,335)
Foetal exposure during pregnancy (1,046)
Somnolence (831)
Completed suicide (723)
Overdose (691)
Condition aggravated (673)
What Other Drugs Cause Depression?
OXYCODONE (6,871)
ADALIMUMAB (6,340)
APREMILAST (5,129)
ACETAMINOPHEN\OXYCODONE (4,035)
ACETAMINOPHEN\HYDROCODONE (3,699)
METHOTREXATE (3,577)
ETANERCEPT (3,538)
LEVONORGESTREL (3,529)
MORPHINE (3,280)
PREDNISONE (3,211)
Which VALPROIC ACID Alternatives Have Lower Depression Risk?
VALPROIC ACID vs VALPROMIDE
VALPROIC ACID vs VALSARTAN
VALPROIC ACID vs VALTREX
VALPROIC ACID vs VAMOROLONE
VALPROIC ACID vs VANCOMYCIN