Depression: Which Medications Cause It? (148,353 Reports Across 1,826 Drugs)
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Depression has been reported as an adverse event with 1,826 different drugs in the FDA's FAERS database, with 148,353 total reports. 5,998 of these reports resulted in death.The drugs most commonly associated with Depression are OXYCODONE, ADALIMUMAB, and APREMILAST.
148,353
Total Reports
1,826
Drugs Involved
5,998
Deaths
32,833
Hospitalizations
49.2 yrs
Average Patient Age
65.7% / 34.3%
Female / Male
Which Drugs Cause Depression Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| OXYCODONE | 6,871 | 3.6% | 1,462 | 1,734 | 855 |
| ADALIMUMAB | 6,340 | 1.3% | 1,108 | 2,451 | 1,099 |
| APREMILAST | 5,129 | 3.8% | 886 | 914 | 832 |
| ACETAMINOPHEN\OXYCODONE | 4,035 | 4.1% | 762 | 890 | 397 |
| ACETAMINOPHEN\HYDROCODONE | 3,699 | 3.4% | 325 | 596 | 38 |
| METHOTREXATE | 3,577 | 1.4% | 1,122 | 1,645 | 1,133 |
| ETANERCEPT | 3,538 | 1.0% | 829 | 1,187 | 869 |
| LEVONORGESTREL | 3,529 | 3.1% | 6 | 1,152 | 193 |
| MORPHINE | 3,280 | 2.7% | 557 | 758 | 220 |
| PREDNISONE | 3,211 | 2.0% | 1,020 | 1,674 | 1,171 |
| TRAMADOL | 3,169 | 4.2% | 776 | 971 | 532 |
| TOFACITINIB | 3,089 | 2.0% | 843 | 1,038 | 834 |
| DULOXETINE | 2,992 | 5.7% | 35 | 458 | 117 |
| ISOTRETINOIN | 2,985 | 8.5% | 34 | 237 | 52 |
| SODIUM OXYBATE | 2,937 | 4.8% | 8 | 414 | 9 |
| RITUXIMAB | 2,761 | 1.6% | 1,121 | 1,544 | 1,148 |
| HYDROMORPHONE | 2,742 | 3.3% | 394 | 652 | 94 |
| LEVOTHYROXINE | 2,549 | 4.1% | 33 | 327 | 48 |
| FINASTERIDE | 2,530 | 16.4% | 83 | 513 | 282 |
| QUETIAPINE | 2,512 | 3.4% | 452 | 1,131 | 364 |