Does METHOTREXATE Cause Depression? 3,577 Reports in FDA Database
Grow Your Own Natural Pharmacy at Home
Medicinal Garden Kit — 10 healing herbs, 4,818 seeds + step-by-step guide.
According to the FDA Adverse Event Reporting System (FAERS), 3,577 reports of Depression have been filed in association with METHOTREXATE (Methotrexate). This represents 1.4% of all adverse event reports for METHOTREXATE.
3,577
Reports of Depression with METHOTREXATE
1.4%
of all METHOTREXATE reports
1,122
Deaths
1,645
Hospitalizations
How Dangerous Is Depression From METHOTREXATE?
Of the 3,577 reports, 1,122 (31.4%) resulted in death, 1,645 (46.0%) required hospitalization, and 1,133 (31.7%) were considered life-threatening.
Is Depression Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 3,577 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Depression?
OXYCODONE (6,871)
ADALIMUMAB (6,340)
APREMILAST (5,129)
ACETAMINOPHEN\OXYCODONE (4,035)
ACETAMINOPHEN\HYDROCODONE (3,699)
ETANERCEPT (3,538)
LEVONORGESTREL (3,529)
MORPHINE (3,280)
PREDNISONE (3,211)
TRAMADOL (3,169)
Which METHOTREXATE Alternatives Have Lower Depression Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA