Does APREMILAST Cause Depression? 5,129 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5,129 reports of Depression have been filed in association with APREMILAST (Otezla). This represents 3.8% of all adverse event reports for APREMILAST.
5,129
Reports of Depression with APREMILAST
3.8%
of all APREMILAST reports
886
Deaths
914
Hospitalizations
How Dangerous Is Depression From APREMILAST?
Of the 5,129 reports, 886 (17.3%) resulted in death, 914 (17.8%) required hospitalization, and 832 (16.2%) were considered life-threatening.
Is Depression Listed in the Official Label?
Yes, Depression is listed as a known adverse reaction in the official FDA drug label for APREMILAST.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Depression?
OXYCODONE (6,871)
ADALIMUMAB (6,340)
ACETAMINOPHEN\OXYCODONE (4,035)
ACETAMINOPHEN\HYDROCODONE (3,699)
METHOTREXATE (3,577)
ETANERCEPT (3,538)
LEVONORGESTREL (3,529)
MORPHINE (3,280)
PREDNISONE (3,211)
TRAMADOL (3,169)
Which APREMILAST Alternatives Have Lower Depression Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA