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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Dependence: Which Medications Are Safest? (86 Drugs Compared)

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86 medications are used for Dependence, with 713 combined adverse event reports. The most reported drugs for Dependence are NALTREXONE and BUPRENORPHINE\NALOXONE.

713
Total Reports
86
Drugs Used

All Medications for Dependence Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
NALTREXONE NALTREXONE HYDROCHLORIDE 271 1,106 2,843 4.3%
BUPRENORPHINE\NALOXONE - 198 1,119 2,872 5.2%
BUPRENORPHINE Buprenorphine and Naloxone 76 25,813 9,467 31.5%
METHADONE METHADONE HYDROCHLORIDE 35 10,719 5,514 40.8%
COCAINE NUMBRINO 8 8,171 3,863 57.5%
NALMEFENE Zurnai 8 77 118 39.1%
NICOTINE Nicotine Polacrilex 8 740 2,031 2.3%
ALCOHOL Advanced Hand Sanitizer 7 15,215 6,310 69.8%
DIAZEPAM Diazepam 7 12,045 13,635 31.6%
TRAMADOL ConZip 7 14,555 19,235 19.2%
ARIPIPRAZOLE Aripiprazole 6 3,863 20,713 5.8%
HERBALS\MITRAGYNINE - 5 524 267 48.1%
OXYCODONE Oxycodone Hydrochloride 5 55,140 21,279 28.9%

View all 86 drugs →

Most Reported Drugs for Dependence

#1 most reported
#2 most reported
#3 most reported