NALMEFENE for Dependence: Side Effects & Safety Data
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There are 8 adverse event reports in the FDA FAERS database where NALMEFENE was used for Dependence.
Most Reported Side Effects for NALMEFENE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Drug ineffective | 66 | 33.5% | 59 | 55 |
| Coma | 47 | 23.9% | 36 | 31 |
| Toxicity to various agents | 43 | 21.8% | 43 | 34 |
| Hypotension | 30 | 15.2% | 22 | 24 |
| Respiratory depression | 25 | 12.7% | 25 | 17 |
| Depressed level of consciousness | 19 | 9.6% | 19 | 15 |
| Hepatotoxicity | 18 | 9.1% | 18 | 10 |
| Acute kidney injury | 15 | 7.6% | 14 | 9 |
| Drug withdrawal syndrome | 15 | 7.6% | 1 | 11 |
| Metabolic acidosis | 14 | 7.1% | 14 | 9 |
| Off label use | 14 | 7.1% | 4 | 12 |
| Cardiac arrest | 13 | 6.6% | 13 | 12 |
| Bradycardia | 12 | 6.1% | 11 | 10 |
| Malaise | 11 | 5.6% | 0 | 8 |
| Myocardial injury | 11 | 5.6% | 11 | 9 |
Other Indications for NALMEFENE
Alcoholism (60)
Toxicity to various agents (59)
Product used for unknown indication (23)
Overdose (9)
Attention deficit hyperactivity disorder (6)
Poisoning deliberate (6)
Self-destructive behaviour (6)
Other Drugs Used for Dependence
NALTREXONE (271)
BUPRENORPHINE\NALOXONE (198)
BUPRENORPHINE (76)
METHADONE (35)
COCAINE (8)
NICOTINE (8)
ALCOHOL (7)
DIAZEPAM (7)
TRAMADOL (7)
ARIPIPRAZOLE (6)