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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

On and off phenomenon: Which Medications Are Safest? (31 Drugs Compared)

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31 medications are used for On and off phenomenon, with 4,183 combined adverse event reports. The most reported drugs for On and off phenomenon are LEVODOPA and CARBIDOPA\LEVODOPA.

4,183
Total Reports
31
Drugs Used

All Medications for On and off phenomenon Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
LEVODOPA L-Dopa 3,861 546 729 8.3%
CARBIDOPA\LEVODOPA - 100 12,844 25,836 22.0%
APOMORPHINE apomorphine hydrocloride 93 372 1,002 4.7%
OPICAPONE ONGENTYS 44 80 305 7.3%
ISTRADEFYLLINE NOURIANZ 42 716 511 14.3%
AMANTADINE Amantadine 35 483 1,579 9.4%
ROTIGOTINE Neupro 34 1,299 1,727 16.6%
PIMAVANSERIN pimavanserin 21 12,352 7,471 26.7%
SAFINAMIDE Xadago 21 30 171 6.9%
CARBIDOPA\ENTACAPONE\LEVODOPA - 17 298 904 12.6%
FOSCARBIDOPA\FOSLEVODOPA - 13 431 1,747 13.6%
PRAMIPEXOLE Pramipexole Dihydrochloride 13 327 2,091 5.4%
RASAGILINE Rasagiline 12 255 961 9.3%
BENSERAZIDE\LEVODOPA - 10 131 1,153 6.5%
ROPINIROLE ropinirole hydrochloride 10 310 1,192 7.3%
SERTRALINE Sertraline Hydrochloride 10 6,889 19,327 11.5%
RIVASTIGMINE Exelon 7 2,232 2,716 24.5%
VENLAFAXINE Venlafaxine Hydrochloride 6 7,521 15,749 15.7%
ZOLPIDEM\ZOLPIDEM - 5 1,996 2,369 33.9%

View all 31 drugs →

Most Reported Drugs for On and off phenomenon

#1 most reported
#2 most reported
#3 most reported